Conduct clinical research trials into effective treatment for Multi-Drug Resistant TB (MDR-TB) and Extremely Drug Resistant TB (XDR-TB); Study participants are recruited from clinics in the greater Cape Town area who have MDR and XDR TB.
Undertake different TB studies investigating new drugs or various combinations of existing TB antibiotics. For some studies participants visit the TASK site for a few hours a day, others are “in-patient studies” where the participants stay for a number of weeks.
TASK Brooklyn has a 25 bed in-patient capacity, and is a well resourced clinical research site with capabilities to effectively undertake complex clinical trials. Based within the grounds of Brooklyn Chest Hospital (a state managed facility) enables access to specialized hospital services, namely:
- Radiography; Audiology; Occupational Therapy; Physiotherapy; Dietetics and Social work
Spacious facilities and amenities for study participants which include:
- Comfortable patient waiting areas; recreational facilities for day patients, meals and refreshments provided to participants, expert, personalized medical care.
- 6 dedicated passenger vehicles to transport participants and work around their daily schedules.
- Experienced and well trained DOT (directly observed therapy) staff who go out to see study participants and work with them in their home environment to support them during their treatment.
- Access controlled and restricted areas for infectious disease control
- CCTV gated controlled access
- Participant areas are ventilated which conform to international standards.
Under the leadership of Principal Investigator (PI) Professor Andreas Diacon, TASK Applied Science conducted the first and largest Bedaquiline clinical trial at this site, that established the efficacy and safety of Bedaquiline in treating Multi Drug Resistant TB. Bedaquiline was the first “new” TB drug in 50 years which brought hope and improved treatment outcomes for thousands of MDR-TB patients in South Africa and across the world.
Renown as one of the highest recruiting centers.
Studies completed at TASK Applied Science Brooklyn Site have been reported in scientific literature.
Study team at this site work closely with prominent international TB alleviation sponsors and is the preferred site for undertaking MDR-TB and XDR-TB studies due to successes in recruiting and accruing study participants.
TASK Brooklyn is an ACTG accredited research site.